Search on: CYSTINE KNOT MINIPROTEINS 
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Descriptor English:   Cystine-Knot Miniproteins 
Descriptor Spanish:   Miniproteínas Nodales de Cistina 
Descriptor Portuguese:   Miniproteínas Nó de Cistina 
Synonyms English:   Knottin
Knottins
Cystine Knot Miniproteins  
Tree Number:   D12.644.132
D12.776.217
Definition English:   A structurally-related family of small proteins that form a stable tertiary fold pattern which is supported by a series of disulfide bonds. The arrangement of disulfide bonds between the CYSTEINE moieties results in a knotted structure which is unique to this family of proteins. 
History Note English:   2011 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54054 
Unique Identifier:   D057771 

Occurrence in VHL:
 

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